BDBM198121 HPOB

SMILES OCCN(C(=O)Cc1ccc(cc1)C(=O)NO)c1ccccc1

InChI Key InChIKey=RFAZNTABYJYOAR-UHFFFAOYSA-N

Data  1 KI  86 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 198121   

TargetHistone deacetylase 11(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human HDAC11 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full-length human HDAC11 expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant HDAC11 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed